Overview
FiveD
Prescan CamEra, Multi-Channel Fluorescence, Objective Switcher, Nvidia Jetson Nano (R) computer
Modules
Enhance the functionality of your Scope
Community-driveN Software
ImSwitch
Modular Microscopy Software
Open-Source
The adaptable System for your modular Idea
Have multiple microscopes side by side to maximise sample through-put
FiveD
Alpha
The INVESTIGATOR Line is designed to elevate your microscopy experience with a premium-quality microscope, equipped with an expansive suite of functionalities to kickstart your journey into the realm of intelligent microscopy. FiveD symbolizes the five adjustable dimensions, allowing you to freely navigate your samples in XYZ, and capture dynamic time-lapse imagery across various channels, including brightfield and widefield fluorescence. Its robust open interface ensures seamless integration with nearly any programming language, complemented by the Python interface within ImSwitch, which consolidates these features into an intuitive framework for responsive microscopy. Intrigued? Reach out to us!
FiveD
Features
Optics
- 4x, NA=0.15 (FOV: 10mm, Res.: 2.3µm)
- 10x, NA=0.3 (FOV: 4mm, Res.: 1.2µm)
- 20x, NA=0.5 (Ph optional, FOV: 2mm, Res.: 0.8µm)
- 60x, NA=0.8 (FOV: 1mm, Res.: 0.5µm)
- 100x, NA=1.25 (oil, FOV: 0.5mm, Res.: 0.3µm)
Illumination (Configurable)
- Bright, Oblique Illumination, Phase-contrast, Darkfield*
- 488nm/635nm Single-Mode Dual-Laser (Fluorescence)
- 488nm or 635nm Single Model Laser (Fluorescence)
Camera
- 12 Mp, USB3.0, Sony IMX226
- Optional: Prescan Camera
Stage (Configurable)
- Option 1: +/-10mm, 0.3nm increment open-loop
- Option 2: 60x80x10mm, 0.3nm increment open-loop
- Option 3 (comming soon): 90x140x10mm, 0.3nm increment open-loop (opt.: 1.5µm closed-loop)
High-Throughput
Adapt to your sample
Discover the latest innovation in microscopy with our new XYZ stage, designed to enhance flexibility for both your application and samples. Effortlessly accommodate standard well-plates, or utilize our customized sample adaptors for seamless integration of any sample holder.
Our microscope sets itself apart by keeping the optics fixed, allowing the sample to move within a stationary focus, offering a unique approach compared to traditional designs. This open-source architecture not only facilitates easy customization but also simplifies the incorporation of additional components like cell incubation chambers.
The XY stage is powered by fastly moving stepper motors, achieving a resolution of ~0.3 µm, complemented by a magnetic encoder that ensures a control feedback loop as precise as 1µm. Moreover, the Z-axis benefits from a dual sub-micrometer precise linear translational stage mechanism, enabling smooth movement of the sample plate. Embrace unparalleled precision and adaptability with our innovative XYZ stage microscope, designed for advanced research needs.
Modular
Customize your scope
The core identity of UC2 lies in its modularity, enabling rapid prototyping and tailored solutions for user-specific and application-specific challenges. This principle extends to the professional range of openUC2, albeit in a refreshed guise.
Compact, monolithic functional modules facilitate the adaptation of cameras for detection, lasers for fluorescence excitation, or autofocus modules for consistently sharp imaging. The hot-plug system allows for quick swapping of functional groups, with the kinematic connection ensuring reproducible, optically stable alignment.
Creativity knows no bounds. Enhance your FiveD’s capabilities with super-resolution, optical sectioning, or FLIM by designing your own module. The upcoming Module Developer Kit (MDK) is designed to seamlessly integrate your innovations into the optical engine, representing a significant advancement for open microscopy, science, and beyond. This open approach not only fosters innovation but also democratizes access to cutting-edge microscopy techniques, paving the way for groundbreaking discoveries across various fields of research.
FLEXIBLE
IMAGE AT DIFFERENT SCALES
There are many paths from the individual lens to the finished microscope.
After our tutorial ends, the adventure really begins. Explore your own environment by taking distributed samples and analyzing them, extend our basic kit with new components or develop your own modules. openUC2 is open-source! You can find all essential design files on Github and extend your existing system as you like. Challenge yourself and extend the toolbox to e.g. detect micro-plastic in drinking water and share it with the growing and very active community!
Core
Curious?
Contact us for
a custom quotation.
Contact us for a custom quotation.
Control
Interface for open workflow interaction
The FiveD microscope can be integrated into your existing workflow. The electronics enable wireless control via a PS4 game controller, USB-serial or Wifi-based interaction via the open-source UC2-REST interface that can be integrated into a variety of different programming languages (a Python API/package is provided as an example), an interactive touchscreen, and a fully supported ImSwitch version that can control the microscope.
The microscope’s REST-API backend can be used directly to implement it as an adapter into an automated workflow including, for example, robotic arms, liquid handling robots or automated imaging pipelines. Curious? Contact us if you would like to learn more!
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